Research Articles

• Boero, L, Wu H, Zak JD, Masset P, Pashakhanloo F, Jayakumar S, Tolooshams, B, Ba D, Murthy VN (2025) Perception and neural representation of intermittent odor stimuli in mice. bioRxiv 2025.02.12.637969 [pdf] 

• Belonio KC**, Haile ES**, Fyke Z, Vivona L, Konanur V, Tulabandhula T, Zak JD (2025) Amplification of olfactory transduction currents implements sparse stimulus encoding Journal of Neuroscience e2008242025 [pdf] **equal contribution

• Fyke Z, Johansson R, Scott AI, Wiley D, Chelsky D, Zak JD, Nakouzi NA, Koster KP, Yoshii A (2024) Reduction of Neuroinflammation and Seizures in a Mouse Model of CLN1 Batten Disease using the Small Molecule Enzyme Mimetic, N-Tert-Butyl Hydroxylamine. Molecular Genetics and Metabolism 143(1-2):108537 [pdf]

• Zak JD†, Reddy G, Konanur V, Murthy VN (2024) Distinct information conveyed to the olfactory bulb by feedforward input from the nose and feedback from the cortex. Nature Communications 15:3268 [pdf]   †corresponding author
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• Zavatone-Veth JA, Masset P, Tong WL, Zak JD, Murthy VN, Pehlevan C (2023) Neural circuits for fast Poisson compressed sensing in the olfactory bulb. Advances in Neural Information Processing Systems 36 [pdf]

• Zak JD, Schoppa NE (2022) Neurotransmitter regulation rather than cell-intrinsic properties shapes the high-pass signal filtering properties of olfactory bulb glomeruli. Journal of Physiology 600.2:393-417 [pdf]

• Zak JD†, Schoppa NE (2021) Optical manipulations reveal strong reciprocal inhibition but limited recurrent excitation within olfactory bulb glomeruli. eNeuro 0311-21.2021  [pdf]   †corresponding author

• Zak JD†, Reddy G, Vergassola M, Murthy VN (2020) Antagonistic odor interactions in olfactory sensory neurons are widespread in freely breathing mice. Nature Communications 11:3350 [pdf]   †corresponding author
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• Gire DH**, Zak JD**, Bourne JN, Goodson N, Schoppa NE (2019) Balancing extrasynaptic excitation and synaptic inhibition within olfactory bulb glomeruli. eNeuro 6(4)0247-19.2019 [pdf]   **equal contribution 

• Albeanu DF, Provost AC, Agarwal P, Soucy E, Zak JD, Murthy VN (2018) Olfactory marker protein (OMP) regulates formation and refinement of the olfactory glomerular map. Nature Communications 9:5073 [pdf]

• Zak JD, Grimaud J, Li R-C, Lin C-C, Murthy VN (2018) Calcium-activated chloride channels clamp odor-evoked spike activity in olfactory receptor neurons. Scientific Reports 8:10600 [pdf]

• Reddy G**, Zak JD**, Vergassola M, Murthy VN (2018) Antagonism in olfactory receptor neurons and its implications for the perception of odor mixtures. eLife 7:e35958 [pdf]   **equal contribution
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• Zak JD, Whitesell JD, Schoppa NE (2015) Metabotropic glutamate receptors promote disinhibition of olfactory bulb glomeruli that scales with input strength. Journal of Neurophysiology 113(6):1907-20 [pdf]

• Gire DH, Franks KM, Zak JD, Tanaka KF, Whitesell JD, Mulligan AA, Hen R, Schoppa NE (2012) Mitral cells of the olfactory bulb are mainly excited through a multi-step signaling path. Journal of Neuroscience 32:2964-75 [pdf]

• Zhang Z-W, Zak JD, Liu H (2010) MeCP2 is required for normal development of GABAergic circuits in the thalamus. Journal of Neurophysiology 103(5):2470-81 [pdf]

Reviews, Commentary, & Chapters

• Saunders CJ, Zak JD (2024) "Chemical senses." In: Kirby ED, Glenn MJ, Sandstrom NJ, Williams CL, eds. Introduction to Behavioral Neuroscience, 1e. Houston, TX: OpenStax, November 2024 [pdf]

• Fyke Z, Belonio KC, Zak JD (2024) Shaping smell: Chloride currents dictate the kinetics of olfactory transduction. Journal of Physiology 602:4699-700 [pdf]

• Zak JD (2022) Longitudinal imaging of individual olfactory sensory neurons in situ. Frontiers In Cellular Neuroscience fncel.2022.946816 [pdf]

• Zak JD**, Wallace J**, Murthy VN (2020) How neuroscience labs can limit their environmental impact. Nature Reviews Neuroscience 21:347-8 [pdf]   Featured on Journal Cover.   **equal contribution
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• Zak JD (2016) A computational framework for temporal sharpening of stimulus input in the olfactory system. Journal of Neurophysiology 115(4):1749-51 [pdf]